Baqsimi is a form of glucagon that is given as a nasal spray. Glucagon is a natural hormone produced by the body that functions by increasing blood sugar via the liver. Glucagon is an active ingredient that has been around for years, but it is now available as the first and only nasal spray used to treat low blood sugar. A recent study published in Diabetes Care stated that intranasal administration of glucagon is just as effective in treating severe hypoglycemia as a glucagon injection.

Anyone who is on insulin is at risk for low blood sugar emergencies, making it important to have a product on hand to reverse the effects. Baqsimi is a great option when oral carbohydrates, sugar, or glucose tablets do not work. It is a single-dose product that is inhaled as a puff through the nose. It is indicated for the treatment of severe hypoglycemia for adults and children ages four and up.

Baqsimi functions by elevating the concentration of glucose in the blood. It works through activating glucagon receptors, Gs? and Gq, in the liver, initiating the breakdown of glycogen and the release of glucose by the liver. In order for glucagon to elicit anti-hypoglycemic effects, there must be glycogen stores in the liver.

Baqsimi is provided as a nasal powder within a device. Each device contains 3 milligrams (mg) of glucagon in a white powder. Each device contains a single dose of glucagon.

Common side effects of Baqsimi Nasal Glucagon Spray include:

Nausea

Vomiting

Headache

Nose discomfort

Runny or stuffy nose

Eye redness

Itchy nose, throat, and eyes

Watery eyes