Buy Glucophage XR 500mg Tablet

Glucophage XR is a biguanide that contains metformin hydrochloride. It is a prescription medication used in addition to diet and exercise to improve glucose control in adults with type II diabetes mellitus (T2DM). Controlling hyperglycemia prevents downstream complications such as kidney damage, loss of limbs, blindness, heart attack, stroke, or nerve problems. It is important that diabetes remains controlled to lessen the chance of related complications. Glucophage XR is not recommended for the treatment of type I diabetes or for patients with diabetic ketoacidosis.

HOW DOES GLUCOPHAGE XR WORK?
Glucophage XR is an antidiabetic agent that works by decreasing basal and postprandial plasma glucose. Metformin lessens absorption of glucose in the intestine, lowers hepatic production of glucose, and increases insulin sensitivity by elevating peripheral glucose utilization. Metformin’s exact mechanism is not well understood, but a few methods have been postulated. These include inhibiting mitochondrial complex I activity, stimulating AMP-activated protein kinase (AMPK), inhibition of glucagon-induced increases in cyclic adenosine monophosphate (cAMP), decreasing activation of protein kinase A (PKA), and effecting gut microbiota. With Glucophage XR, insulin secretion does not change, however, all-day plasma insulin response cand fasting insulin levels can decrease.

SIDE EFFECTS
Common side effects include:

Diarrhea
Flatulence
Nausea and vomiting
Vitamin B12 deficiency
Dyspepsia
Asthenia
Abdominal distress
Headache
Heartburn
Loss of appetite
Bloating or gas
Belching
Fullness or loss of appetite