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What is Pyrophenidone

2-phenyl-2-(pyrrolidin-1-yl)-1-(p-tolyl)ethanone is a compound structurally derived Pyrovaleron also known as Centroton, 4-Methyl-β-ketone-prolintane, Thymergix and O-2371. 2-phenyl-2-(pyrrolidin-1-yl)-1-(p-tolyl)ethanone, under research conditions have shown some stimulant properties which could act as a norepinephrine-dopamine reuptake inhibitor (NDRI). The alkyl in 3-position has been replaced with an aromatic system, here it is benzene.

The physiological and toxicological properties of this compound have not been studied.

2-phenyl-2-(pyrrolidin-1-yl)-1-(p-tolyl)ethanone may be utilised by researchers who wish to use it as a reference sample for their GC/MS, FTIR or NMR analysis catalogues.

Laboratory Procedures

For long term storage, we suggest that 2-phenyl-2-(pyrrolidin-1-yl)-1-(p-tolyl)ethanone be stored at -20°C. It should be stable for at least two years.

2-phenyl-2-(pyrrolidin-1-yl)-1-(p-tolyl)ethanone is supplied as a white crystalline solid. 22-phenyl-2-(pyrrolidin-1-yl)-1-(p-tolyl)ethanone is soluble in organic solvents such as methanol, DMSO, and dichloromethane (DCM), which should be purged with an inert gas. The solubility of 2-phenyl-2-(pyrrolidin-1-yl)-1-(p-tolyl)ethanone in ethanol and DMF is about 18 mg/ml and approximately 16 mg/ml in DMSO.

Further dilutions of the stock solution into aqueous buffers or isotonic saline should be made prior to performing experiments. Ensure that the residual amount of organic solvent is insignificant, since organic solvents may have physiological effects at low concentrations. Organic solvent-free aqueous solutions 2-phenyl-2-(pyrrolidin-1-yl)-1-(p-tolyl)ethanone can be prepared by directly dissolving the crystalline solid in aqueous buffers. The solubility 2-phenyl-2-(pyrrolidin-1-yl)-1-(p-tolyl)ethanone in PBS, pH 6.9, is approximately 18 mg/ml. We do not recommend storing the aqueous solution for more than one day.

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Specifications
Synonyms 2-phenyl-2-(pyrrolidin-1-yl)-1-(p-tolyl)ethanone
IUPAC 2-phenyl-2-(pyrrolidin-1-yl)-1-(p-tolyl)ethanone
PubChem N/A
Cas# N/A
Molecular Formula C19H21NO
Purity 99%
Forumlation / Appearance White Crystal Powder