Buy Actoplus Met XR
WHAT IS ACTOPLUS MET XR?
ACTOplus Met XR (Pioglitazone Hydrochloride and Metformin Hydrochloride) is a combination tablet. It contains pioglitazone hydrochloride and metformin hydrochloride that is presented as an extended-release formulation. Both these drugs are used for the management of type 2 diabetes mellitus. They are taken orally and help to reduce blood glucose levels.
HOW DOES ACTOPLUS MET XR WORK?
ACTOplus Met XR contains pioglitazone. Pioglitazone acts by increasing the sensitivity to insulin in the fat tissue and the muscles. It also decreases the liver’s production of glucose. This has the effect of reducing the levels of circulating insulin and reducing the body’s glucose levels.
ACTOplus MET XR contains metformin. Metformin improves the body’s tolerance for glucose by reducing the absorption of glucose of the intestine, lowering the production of glucose in the liver, and improving the peripheral uptake and use of glucose.
WHAT ARE THE INDICATIONS FOR ACTOPLUS MET XR?
ACTOplus Met XR is indicated for the treatment of patients with type 2 diabetes mellitus. It is used together with diet control and exercise to improve blood glucose levels in adults.
WHAT IS THE DOSE OF ACTOPLUS MET XR?
ACTOplus MET XR comes as a combination of 15 mg pioglitazone and 1000 mg metformin, as well a combination of 30 mg pioglitazone and 1000 mg metformin. As a starting dose ACTOplus MET XR should be taken once a day – either the 15/1000 mg or the 30/1000 mg tablet. In patients who are not responding to the starting dose, the dosage can be increased to 15/1000 mg or 30/1000 mg twice a day. Dose titration should be done while watching for adverse events – particularly those of cardiac failure.