Buy Avandamet Online
Buy Avandamet Online is an oral anti-diabetic drug composed of 2 medications, metformin and rosiglitazone maleate. In combination, these drugs work to control blood sugar levels in patients with type-2 diabetes. Avandamet is intended to be used in combination with diet and exercise.
How does Avandamet work?
The 2 medications in Avandamet (metformin and rosiglitazone maleate), work in different but complementary ways. Metformin belongs to the class of medications called biguanides. This drug works by reducing the amount of glucose produced by the liver and by slowing the breakdown of carbohydrates. Rosiglitazone, however, belongs to the class of medications called thiazolidinediones, and works by allowing more glucose to enter fat, muscles, and the liver. In combination, these 2 medications work as a team to control blood sugar levels.
Avandamet comes in the following dosages and strengths:
2 mg/500 mg
4 mg/500 mg
2 mg/1000 mg
4 mg/1000 mg
The dose should be started at 2 mg/500 mg once or twice a day, and increased per patient tolerance and individualization. If blood sugar is not well controlled after 4 weeks, the dosage can be increased by 2 mg/500 mg until adequate control is achieved. For metformin, it can take 1-2 weeks to assess the effects of a dose increase. For rosiglitazone, it can take up to 12 weeks to assess the effects of a dose increase. Gradual escalation is recommended to find the minimum effective dose.
The daily dose should not exceed 8 mg of rosiglitazone and 2000 mg of metformin.
Overdose of rosiglitazone is not well documented. Metformin overdose, however, can cause lactic acidosis and can be deadly if not treated. Early symptoms of metformin overdose are vague and include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. Advanced symptoms are low blood pressure, kidney failure, and cardiac arrest. Dialysis may be indicated to clear excess metformin from the body.
If immediate help is required, call 911. If overdose is suspected, call poison control at 800-222-1222.
If you experience signs or symptoms of an allergic reaction, such as hives, rash, itching, difficulty breathing, or swelling of the face, mouth, or throat, seek immediate medical attention.
The most common side effects of Avandamet include:
Tell your doctor if you notice:
Symptoms of heart failure such as shortness of breath with activity, difficulty breathing when lying flat, significant swelling, cough, etc.
Symptoms of liver dysfunction such as abdominal pain, dark urine, yellow skin, and loss of appetite.
Get medical help immediately if you suspect diabetic ketoacidosis. DKA is a dangerously high blood sugar level in combination with the presence of ketones in your blood or urine. Symptoms of DKA include fruity-smelling breath, fast, deep breathing, and excessive thirst or urination.
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